Attended conferences

XXVI Conference of Young SIF Pharmacologists (Bologna)

Marcella Palumbo - oral presentation "Effect of elexacaftor/tezacaftor/ivacaftor therapy on serum lipoprotein functions in adults with cystic fibrosis" M. Palumbo, C. Greco, F. Zimetti, M. P. Adorni, M. Ruscica, F. Blasi, A. Gramegna.

Avogadro Colloquia - 6th edition (Roma)

"Nanomedicines and Drug Repurposing" - Ruggero Bettini, Invited talk.

39° Congresso Nazionale SISA (Roma)

• Martina Ugolotti - oral presentation "Investigating PCSK9 as a therapeutic target in Alzheimer's disease: evidence from patient-derived astrocytes" M. Ugolotti, B. Papotti, M.P. Adorni, M.G. Martina, L. Giannessi, A. Olejnik, S.M. Bell, H. Mortiboys, M. Radi, F. Zimetti.
• Marcella Palumbo - oral presentation "Cerebrospinal fluid and plasma HDL (dys)function in Multiple Sclerosis" M. Palumbo, M. Ugolotti, M. Minetti, E. Curti, F. Bernini, F. Granella, F. Zimetti, M. P. Adorni.
• Bianca Papotti - oral presentation "New Small Molecules Inhibitors Of Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) As Potential Pharmacological Tool In Alzheimer’s Disease: In Vitro Studies" - B. Papotti, M. Ugolotti, M. P. Adorni, L. Giannessi, M.G. Martina, M. G. Lupo, N. Ferri, M. Radi, F. Bernini, I. Zanotti, F. Zimetti.

8th BRAYN (Brainstorming Research Assembly For Young Neuroscientists) Conference 2025 (Torino)

• Marcella Palumbo - speed talk and poster presentation "Cerebrospinal fluid and plasma HDL (dys)function in Multiple Sclerosis" M. Palumbo, M. Ugolotti, M. Minetti, E. Curti, F. Bernini, F. Granella, F. Zimetti, M. P. Adorni.
• Bianca Papotti  - poster presentation "New Small Molecules Inhibitors Of Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) As Potential Pharmacological Tool In Alzheimer’s Disease: In Vitro And In Vivo Studies" - B. Papotti, M. Ugolotti, B. Mattina, M. Palumbo, M. P. Adorni, L. Giannessi, P. Bonicco, M. G. Lupo, F. Vacondio, F. Potì, N. Ferri, M. Radi, F. Bernini, I. Zanotti, F. Zimetti.

23rd International Symposyum on Microencapulation (Ferrara)

• "Oral drug delivery with Macro-Micro-Nano systems" - Ruggero Bettini, Invited Lecture.
• "Overcoming barriers in ocular drug delivery: potential and challenges of nanocarriers" - Sara Nicoli, Invited Lecture.

Congresso Regionale SISA, Sezione Tosco-Emiliana (Ferrara)

• Marcella Palumbo (post-doctoral researcher) - oral presentation "Valutazione della (dis)funzione delle HDL del fluido cerebrospinale e del siero nella sclerosi multipla"
• Beatrice Mattina (PhD student) - oral presentation "Valutazione della sicurezza e della biodistribuzione di nuovi inibitori sintetici di PCSK9 in topi C57BL/6"

38° Congresso Nazionale della Società Italiana per lo Studio dell'Aterosclerosi (SISA) (Bologna)

• Dietary flavan-3-ol metabolites modulate proinflammatory human fibroblast activation in vitro: potential perspectives in the prevention of CVD - Beatrice Mattina, Claudio Curti, Pedro Miguel Parreno Mena, Claudia Favari, Ilaria Zanotti, Nicoletta Ronda - poster presentation of Beatrice Mattina, PhD Student
• Cerebrospinal fluid and plasma HDL (dys)function in Multiple Sclerosis - Marcella Palumbo, Martina Ugolotti, Matteo Minetti, Erica Curti, Franco Bernini, Franco Granella, Maria Pia Adorni, Francesca Zimetti - poster presentation of Marcella Palumbo, PhD
• Influence of the ApoE4 genotype on PCSK9-lipids association in cerebrospinal flud and serum of patients in the Alzheimer's Disease continuum - Bianca Papotti, Marcella Palumbo, Maria Pia Adorni, Lisa Elviri, Annalisa Chiari, Manuela Tondelli, Roberta Bedin, Enrica Baldelli, Giulia Lancellotti, Maria Giovanna Lupo, Nicola Ferri, Marco Bertolotti, Franco Bernini, Chiara Mussi, Francesca Zimetti - oral presentation of Bianca Papotti, PhD
• PCSK9 inhibition as a potential strategy to treat Alzheimer's Disease: in vitro and in vivo studies - Martina Ugolotti, Bianca Papotti, Beatrice Mattina, Ilaria Zanotti, Maria Pia Adorni, Lisa Giannessi, Ilaria Rossi, Maria Giovanna Lupo, Nicola Ferri, Antonietta Vilella, Marco Radi, Franco Bernini, Francesca Zimetti - oral presentation of Martina Ugolotti, PhD Student

42° Congresso Nazionale della Società Italiana di Farmacologia (SIF) (Sorrento - NA)

• Marcella Palumbo (post-doctoral researcher) - oral presentation "EFFECT OF A DIET SUPPLEMENTATION WITH LXR AGONISTS-CONTAINING HIMANTHALIA ELONGATA AND SARGASSUM FUSIFORME EXTRACTS ON COGNITIVE FUNCTION IN AD MICE MODELS"
• Bianca Papotti (post-doctoral researcher) - oral presentation "PCSK9 INHIBITION AS A POTENTIAL PHARMACOLOGICAL STRATEGY TO TREAT ALZHEIMER'S DISEASE: IN VITRO AND IN VIVO STUDIES"
• Martina Ugolotti (PhD student) - poster presentation "IN VITRO AND IN VIVO NEUROPROTECTIVE EFFECTS OF MAGNOFLORINE: POTENTIAL IMPLICATION FOR ALZHEIMER'S DISEASE"
• Beatrice Mattina (PhD student) - poster presentation "DIETARY FLAVAN-3-OL METABOLITES MODULATE PROINFLAMMATORY HUMAN FIBROBLAST ACTIVATION IN VITRO: POTENTIAL PERSPECTIVED IN THE PREVENTION OF CVD"
  

CRS 2024 Annual Meeting & Exposition "Integrating Delivery Science Across Disciplines" (Bologna)

"Advanced ex vivo ocular models: essential tools in ophthalmic formulation development"

Oral presentation: Silvia Pescina

7th NANOMED Erasmus mundus joint master degree workshop "Nanomedicines for alternative drug delivery routes" (Angers, France)

"Imaging techniques in the development of nanomedicines intended for ocular and topical routes of administration"

Oral presentation: Silvia Pescina

ULLA Summer School (Leiden, The Netherlands)

"Effect of PCSK9 inhibition on Alzheimer’s disease-related parameters in human cerebral cell models" (M. Ugolotti, B. Papotti, L. Giannessi, M. Radi, F. Bernini, F. Zimetti et al.) - Poster presentation of Martina Ugolotti, PhD student.

VII Giornata della Ricerca del Centro E. Grossi Paoletti "DALLE LIPOPROTEINE ALLE DISLIPIDEMIE: PROSPETTIVE ATTUALI E FUTURI ORIZZONTI" (Milano)

"The complex relationship between cholesterol and neurodegenerative diseases: focus on HDL and multiple sclerosis" - Presentation of Marcella Palumbo, PhD student.

7° Forum SIRC "New Roads in Cardiovascular Research" (Parma)

"Serum lipoprotein dysfunction is a major determinant and independent clinical marker of coronary atherosclerosis and high cardiovascular risk in patients with rheumatoid arthritis" - (Palumbo Marcella, Papotti Bianca, Ugolotti Martina,  Zimetti Francesca, Bernini Franco, Ronda Nicoletta et al.). Poster presentation of Marcella Palumbo, PhD student.

Congresso InterRegionale SISA Tosco-Emiliana (Arezzo)

• "Metabolismo lipidico e neurodegenerazione" - (F. Zimetti, M.P. Adorni) - Poster presentation
• "Inibizione di PCSK9 come potenziale strategia terapeutica per il trattamento della malattia di Alzheimer: studi in vitro e in vivo" - oral presentation of Martina Ugolotti, PhD student.
• "Gli estrogeni endogeni si associano a protezione cardiovascolare nei pazienti con artrite reumatoide" - (Bianca Papotti, Marcella Palumbo, Martina Ugolotti, Nicoletta Ronda, et al.). Oral presentation of Bianca Papotti, PhD student.

92° Congresso Europeo dell'Aterosclerosi - European Atherosclerosis Society (Lyon, France)

• "Proprotein convertase subtilisin/kexin type 9 (PCSK9) genetic deletion attenuates amyloid-β pathology, neuroinflammation and improves cognitive functions in an Alzheimer’s disease mouse model". (B. Papotti, F. Zimetti, I. Zanotti, G. Remaggi, L. Elviri, F. Bernini et al.) - Poster presentation of Bianca Papotti, PhD student.
• "Effect of natural and synthetic PCSK9 inhibitors on Alzheimer’s disease-related parameters in human cerebral cell models". (M. Ugolotti, B. Papotti, M.P. Adorni, L. Giannessi, M. Radi, F. Bernini, F. Zimetti, et al.) - Poster presentation of Martina Ugolotti, PhD student.
• "Identification of new side chain oxidized sterols as novel liver X receptor agonists with therapeutic potential in the treatment of cardiovascular and neurodegenerative diseases" (M. Palumbo, F. Zimetti, M. P. Adorni, et al.) - Poster presentation of Marcella Palumbo, PhD student.

Annual Conference of European Association of Faculties of Pharmacy (EAFP 2024) (Bergen, Norway)

“Blended intensive programs: a learning experience in higher education”. (Silvia Pescina, Stefano Bruno, Theonil Lugo-Arrendell, Marco Pieroni, Fabio Sonvico, Ilaria Zanotti) - Poster Presentation: Prof. Silvia Pescina

Gordon Research Conference on Lipidomics - Barga (LU), Italy
"Glucosylceramide synthase inhibition delays the onset of acquired resistance in NSCLC models in the era of OSIMERTINIB". (Galvani, F; Viglioli, M; Vacondio, F; Rivara, S; Lodola, A; Mor, M. et al.) - Poster Presentation of Francesca Galvani, PhD.

17th edition of the EUROPEAN SYMPOSIUM ON CONTROLLED DRUG DELIVERY (ESCDD2024) - Egmond Aan Zee (NL)
"Influence of PEG chain length on the properties of TPGS micelles for ocular drug delivery" (Sara Signorini, Caterina Ricci, Elena Del Favero, Cristina Padula, Silvia Pescina, Patrizia Santi, Sara Nicoli) - Poster Presentation of Sara Signorini, PhD.

Seminario "Invecchiamento patologico e malattia di Alzheimer: stato dell'arte della ricerca a Parma" (Parma): "Metabolismo del colesterolo e malattia di Alzheimer: dalle evidenze scientifiche allo sviluppo terapeutico" - Prof. Franco Bernini, Prof.ssa Francesca Zimetti - Lettura su invito.

14th World Meeting in Pharmaceutics and Biopharmaceutics and Pharmaceutical Technology (Vienna)

• Sodium hyaluronate nanoparticles for lung delivery of amphotericin B in cystic fibrosis (Laura Bertocchi, Annalisa Bianchera, Ruggero Bettini) - Poster Presentation of Prof. Annalisa Bianchera.
• Imiquimod solubility in different solvents: an interpretative approach (Daisy Sorgi, Andrea Sartori, Saveria Germani, Rosita Nicolella Gentile, Annalisa Bianchera, Ruggero Bettini) - Poster Presentation of Daisy Sorgi, PhD.
• Biodegradable materials for improving oral absorption of carbamazepine: an eco - sustainable approach (Eride Quarta, Annalisa Bianchera, Ruggero Bettini) - Poster Presentation of Dr. Eride Quarta, PhD.

37° Congresso Nazionale della Società Italiana per lo Studio dell'Aterosclerosi (Napoli): "PCSK9 genic deletion attenuates Amyloid - β pathology , neuroinflammation and improves cognitive functions in an Alzheimer’s Disease Mouse Model" (B. Papotti, A. Vilella, M. Bodria , F. Zimetti, I. Zanotti, G. Remaggi, L. Elviri, F. Potì , M.G. Lupo, E. Daini, E. Vandini, M. Zoli, N. Ferri, D. Giuliani, F. Bernini) - Oral presentation of Bianca Papotti, PhD student.

Convegno monotematico SIF (Parma):

• "In vitro and in vivo studies on novel PCSK9 inhibitors as pharmacological approach for hypercholesterolemia" (Martina Ugolotti, Bianca Papotti, Francesca Zimetti, Beatrice Mattina, Ilaria Zanotti, Lisa Giannessi, Lisa Elviri, Marco Radi, Franco Bernini et al.) - Oral presentation of Martina Ugolotti, Ph.D. student.
• "Identification of New Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular Diseases" (Marcella Palumbo, Francesca Zimetti, et al.) - Poster Presentation of Marcella Palumbo, PhD student.

XXVIII National Meeting on Medicinal Chemistry (Chieti):

• "QM/MM modelling of MGL carbamoylation by piperazine azole ureas reveals the role of leaving group expulsion and discriminates inhibitors with high and low potency" - Poster Presentation of Francesca Galvani, PhD.
• "Targeting Glucosylceramide Synthase To Fight Resistance To Osimertinib In Non-Small Cell Lung Cancer" - Poster Presentation of Martina Viglioli, PhD.

20th National Congress of the Italian Society for Neuroscience (Turin - Centro Congressi Lingotto): "PCSK9 as a potential new player in Alzheimer’s disease" Prof. Francesca Zimetti - Invited lecture

PhD student National Meeting in Neuroscience (Torino): "Novel PCSK9 inhibitors as pharmacological approach to treat Alzheimer's disease" (Martina Ugolotti, Bianca Papotti, Francesca Zimetti, Beatrice Mattina, Ilaria Zanotti, Lisa Giannessi, Lisa Elviri, Marco Radi, Franco Bernini, et al.) - Poster Presentation of Martina Ugolotti, PhD.

46^th European Lipoprotein Club Annual Scientific Meeting (Tutzing, Germany):

• "Identification of two new Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases" (Marcella Palumbo, Francesca Zimetti et al.) - Presentation of Marcella Palumbo, PhD.
• "PCSK9 genetic deletion attenuates Aβ pathology, neuroinflammation and improves cognitive functions in an Alzheimer’s disease mouse model" (Bianca Papotti, Francesca Zimetti , Ilaria Zanotti, Giulia Remaggi, Lisa Elviri, Franco Bernini et al.) - Presentation of Bianca Papotti, PhD.

EUROPIN Summer School on Drug Design (Vienna, Austria):

• "Multiscale simulations for the design of new MGL inhibitors" - Presentation of Francesca Galvani, PhD.
  
• "Enzymes degrading endogenous lipid mediators as anti-inflammatory targets. The case study of N-acylethanolamine acid amidase" - Presentation of Dr. Laura Scalvini, University researcher.

XXV Conference of Young SIF Pharmacologists (Urbino PU): "In vitro and in vivo studies on novel PCSK9 inhibitors as pharmacological approach to treat Alzheimer’s disease" (Martina Ugolotti, Bianca Papotti, Francesca Zimetti, Beatrice Mattina, Ilaria Zanotti, Lisa Giannessi, Lisa Elviri, Marco Radi, Franco Bernini, et al.) - Poster Presentation of Martina Ugolotti, PhD.

Symposium on the Longevity Factor HDL (Seoul, South Korea): "HDL and Cerebral Cholesterol Metabolism: Novel Target in Neurodegenerative Disorders" - Speech of Prof. Francesca Zimetti, Invited Speaker.

International Symposium on Research Advances in Global Health (SYMGLOH - Paris): "Inhalable powders for fighting infectious diseases" - Intervento del Prof. Ruggero Bettini

ULLA Workshop 2023 – “Stem cell therapy - from basics to ATMPs” (University of Leiden): "In vitro and in vivo studies on novel PCSK9 inhibitors as pharmacological approach for the treatment of Alzheimer’s disease" (Martina Ugolotti, Bianca Papotti, Francesca Zimetti, Beatrice Mattina, Ilaria Zanotti, Lisa Giannessi, Lisa Elviri, Marco Radi, Franco Bernini et al.)

Congresso Regionale SISA Sezione Tosco-Emiliana - Bologna: "La delezione genica di PCSK9 attenua la deposizione di placche amiloidi, la neuroinflammazione e migliora le funzioni cognitive in un modello murino di malattia di Alzheimer" (Bianca Papotti, Francesca Zimetti , Ilaria Zanotti, Giulia Remaggi, Lisa Elviri, Franco Bernini et al.)

62° Simposio AFI - Rimini: "Polveri per inalazione" - Intervento del Prof. Ruggero Bettini

EUFEPS annual meeting - University of Lisbon (Portugal):

• "New inhalation drug delivery systems for the treatment of pulmonary fibrosis" (Gianluca Bazzoli, Annalisa Bianchera, Ruggero Bettini) - POSTER
• "Biodegradable Materials For Improving Oral Absorption Of Carbamazepine: An Eco - sustainable Approach" (Eride Quarta - PhD) - Poster
  

Convegno digitale di Scienza e Tecnologia lattiero-casearia: "Dal latte al formaggio stagionato, dai microbi ai peptidi che fanno buono il formaggio, verso un tesoro di composti bioattivi" - Intervento scientifico/divulgativo della Prof.ssa Benedetta Bottari

2023 HDL Workshop – Infection and Neurodegenerative Diseases - Boston, MA, USA: "HDL and Brain Lipid Metabolismin Alzheimer’s Disease" - Intervento della Prof.ssa Francesca Zimetti